Prolonged dystonic reaction to chlorpromazine in myxoedema coma.

Prolonged dystonic reaction to chlorpromazine in myxoedema coma.

A case of myxoedema coma is reported where the administration of chlorpromazine resulted in a prolonged dystonic reaction. A similar challenge with a butyrophenone when the patient was on thyroxine caused a similar but much abbreviated response.

Respiratory acidosis in hypothermic myxoedema coma.

Myxoedema coma presenting in status epilepticus.

A 71-year-old woman with myxoedema coma presenting in status epilepticus is reported. Although this complication of myxoedema coma is considered to be fatal the patient described responded dramatically to treatment and remains in good health.

Predictors of outcome in myxoedema coma

Myxoedema coma is a rare and life-threatening illness the outcome of which has not been robustly studied in large numbers, partly due to its low incidence. Dutta and colleagues have explored outcome predictors in a developing country where access to thyroid function tests is more limited than in the Western world. Cardiovascular instability, reduced consciousness, persistent hypothermia, and se...

Hypothyroidism in the elderly: heralding myxoedema coma

Progress in Neurology and Psychiatry July/August 2016 www.progressnp.com 12 Thyroid disorders in the elderly population can present challenges to the t rea t ing team, both in terms of diagnosis and management. In iodinereplete communities, the prevalence of spontaneous hypo thyroidism is between 1 and 2%; it is more common in older women and is 10 times more common in women than in men.1 Numer...